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Article

FOXM1-regulated ZIC2 promotes the malignant phenotype of renal clear cell carcinoma by activating UBE2C/mTOR signaling pathway.

International journal of biological sciences - 1 Jan 2023

Lv Zhengtong, Wang Miao, Hou Huimin, Tang Guyu, Xu Haozhe, Wang Xuan, Li Yuan, Wang Jianye, Liu Ming

Abstract excerpt

Background: As a transcription factor, Zic family member 2 (ZIC2) has been involved in more and more studies of tumorigenesis, which has been proved by our research team to be an effective prognostic marker for Pan-cancer. However, the prognosis, tumor promoting effect and regulatory mechanism of ZIC2 in clear cell renal cell carcinoma (ccRCC) are still unknown. Methods: The potential clinical significance of...

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Source

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Identifiers

PMID: 37496990
DOI: 10.7150/ijbs.84067
PMCID: PMC10367559

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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