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Article

Establishment of induced pluripotent stem cells derived from patients and healthy siblings of a nevoid basal cell carcinoma syndrome family.

In vitro cellular & developmental biology. Animal - 1 Jun 2023

Nakase Yoji, Hamada Atsuko, Obayashi Fumitaka, Kitamura Naoya, Hata Tsuyoshi, Yamamoto Tetsuya, Okamoto Tetsuji

Abstract excerpt

It is known that a nevoid basal cell carcinoma syndrome (NBCCS) is characterized by a combination of developmental abnormalities and a predisposition to form various tumors. Although it is possible to create disease models via gene editing, there are significant potential problems with this approach such as off-target mutations and differences in SNPs. On the other hand, since disease families share common SNPs,...

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Identifiers

PMID: 37460876
DOI: 10.1007/s11626-023-00778-y
PMCID: PMC10374668

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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