Augmented oxidative stress, accumulation of DNA damage and impaired DNA repair mechanisms in thrombotic primary antiphospholipid syndrome

Abstract excerpt

Antiphospholipid syndrome (APS) is a rare autoimmune disorder with complex pathogenesis. Studies have shown that oxidative stress may contribute to APS pathophysiology. In peripheral blood mononuclear cells (PBMCs) from thrombotic Primary APS (thrPAPS) patients and age/sex-matched healthy controls (HC), as well as a control group of asymptomatic antiphospholipid antibody (aPL) positive individuals without APS...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Renal Diseases and Glomerulopathies
• Share to Systemic Lupus Erythematosus Research
• Share to T-cell and B-cell Immunology