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African swine fever virus protein p17 promotes mitophagy by facilitating the interaction of SQSTM1 with TOMM70

13 Jul 2023

Abstract excerpt

Viruses have developed different strategies to hijack mitophagy to facilitate their replication. However, whether and how African swine fever virus (ASFV) regulates mitophagy are largely unknown. Here, we found that the ASFV-encoded p17 induced mitophagy. Coimmunoprecipitation/mass spectrometry assays identified translocase of outer mitochondrial membrane 70 (TOMM70) as the protein that interacted with p17. The...

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PMID: 37442088
DOI: 10.1080/21505594.2023.2232707

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