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Article

Structural insights into pink-eyed dilution protein (Oca2).

Bioscience reports - 26 Jul 2023

Mesdaghi Shahram, Murphy David L, Simpkin Adam J, Rigden Daniel J

Abstract excerpt

Recent innovations in computational structural biology have opened an opportunity to revise our current understanding of the structure and function of clinically important proteins. This study centres on human Oca2 which is located on mature melanosomal membranes. Mutations of Oca2 can result in a form of oculocutanous albinism, which is the most prevalent and visually identifiable form of albinism. Sequence...

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Identifiers

PMID: 37431738
DOI: 10.1042/BSR20230060
PMCID: PMC10372470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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