Article
Impact of genotype on clinical course in sickle cell disease and the utility of neutrophil-lymphocyte ratio: a ten-year single-institution experience.
Expert review of hematology - 1 Jan 2000
Mathavan Akash, Mathavan Akshay, Mathavan Mohit, Krekora Urszula, Winer Aaron J, Altshuler Ellery, Wnek Russell, Hones Keegan, Thaper Arushi, Artola Richard, Pucci Logan, Haley Patrick, Carter Del, Snead William, Manfrini Denise, Leach Daniel F, DeLaune Jess D, Mandernach Molly W
Abstract excerpt
BACKGROUND: Sickle cell disease (SCD) is a diverse group of blood disorders with significant global disease burden. Contemporary interest in the underlying inflammatory paradigm of SCD has emphasized the role of the neutrophil-lymphocyte ratio (NLR) as a prognostic inflammatory marker. METHODS: We retrospectively reviewed 268 hospitalized patients with SCDs of different genotypes (HbSS, HbSβ0 thalassemia, HbSβ+...
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