Biomarkers for the diagnosis and phenotyping of acute chest syndrome in patients with sickle cell disease.

Abstract excerpt

INTRODUCTION: Acute Chest Syndrome (ACS) is a serious and often fatal complication of Sickle Cell Disease (SCD). In the absence of specific biomarkers that indicate the development of ACS, diagnosis can be nebulous and difficult. In this narrative literature review, we examine the current evidence for novel biomarkers associated with acute and long-term propensity toward ACS. AREAS COVERED: A search focused on...

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• Anemia, Sickle Cell
• Biomarkers
• SCD gene
• Phenotype