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Article

RPL27 contributes to colorectal cancer proliferation and stemness via PLK1 signaling

29 Jun 2023

Abstract excerpt

Although expression of ribosomal protein L27 (RPL27) is upregulated in clinical colorectal cancer (CRC) tissue, to the best of our knowledge, the oncogenic role of RPL27 has not yet been defined. The present study aimed to investigate whether targeting RPL27 could alter CRC progression and determine whether RPL27 gains an extra‑ribosomal function during CRC development. Human CRC cell lines HCT116 and HT29 were...

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Identifiers

PMID: 37387446
DOI: 10.3892/ijo.2023.5541

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