Analyses of whole-genome sequences from 185 North American Thoroughbred horses, spanning 5 generations.

Abstract excerpt

Whole genome sequences (WGS) of 185 North American Thoroughbred horses were compared to quantify the number and frequency of variants, diversity of mitotypes, and autosomal runs of homozygosity (ROH). Of the samples, 82 horses were born between 1965 and 1986 (Group 1); the remaining 103, selected to maximize pedigree diversity, were born between 2000 and 2020 (Group 2). Over 14.3 million autosomal variants were...

Topics

• Animals
• Horses
• Whole Genome Sequencing
• Polymorphism, Single Nucleotide
• Pedigree
• Inbreeding
• Homozygote
• North America
• Male
• Female
• Genome
• Genetic Variation