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Article

Genetic variants in epoxyeicosatrienoic acid processing and degradation pathways are associated with gestational diabetes mellitus.

Nutrition journal - 28 Jun 2023

Lai Siyu, Yan Dandan, Xu Jie, Yu Xiangtian, Guo Jingyi, Fang Xiangnan, Tang Mengyang, Zhang Rong, Zhang Hong, Jia Weiping, Luo Mingjuan, Hu Cheng

Abstract excerpt

AIM: To explore the genetic effects of CYP2C8, CYP2C9, CYP2J2, and EPHX2, the key genes involved in epoxyeicosatrienoic acid processing and degradation pathways in gestational diabetes mellitus (GDM) and metabolic traits in Chinese pregnant women. METHODS: A total of 2548 unrelated pregnant women were included, of which 938 had GDM and 1610 were considered as controls. Common variants were genotyped using the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37370090
DOI: 10.1186/s12937-023-00862-9
PMCID: PMC10303330

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