Article
CYP2E1 C-1054T and 96-bp I/D genetic variations and risk of gestational diabetes mellitus in chinese women: a case-control study.
BMC pregnancy and childbirth - 1 Jun 2023
Pu Yifu, Liu Qingqing, Hu Kaifeng, Liu Xinghui, Bai Huai, Wu Yujie, Zhou Mi, Fan Ping
Abstract excerpt
BACKGROUND: Cytochrome P450 2E1 (CYP2E1) plays a key role in the metabolism of xenobiotic and endogenous low-molecular-weight compounds. This study aimed to determine if the genetic variations of 96-bp insertion/deletion (I/D) and C-1054T (rs2031920) in CYP2E1 were associated with the risk of gestational diabetes mellitus (GDM). METHODS: CYP2E1 polymorphisms were genotyped in a case-control study of 1,134 women...
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