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Article

TWF1 induces autophagy and accelerates malignant phenotype in lung adenocarcinoma via inhibiting the cAMP signaling pathway.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 2023

Wang Yu, Zuo Ran, Huo Gengwei, Han Zhiqiang, He Yuchao, Luo Yi, Chen Liwei, Li Guangtao, Cui Jinfang, Zhu Fuyi, Yue Ping, Yuan Dongqi, Sun Yi, Li Zhaoyue, Chen Peng, Guo Hua

Abstract excerpt

Many studies have shown that the actin cytoskeleton plays an essential role in the initiation and progression of cancer. As an actin-binding protein, Twinfilin1 (TWF1) plays an important role in regulating cytoskeleton-related functions. However, little is known about the expression and function of TWF1 in human tumors. The present study aimed to investigate the functional roles and the underlying molecular...

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Identifiers

PMID: 37358822
DOI: 10.1096/fj.202300248R

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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