Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tuberous sclerosis complex mutations in patients with pancreatic neuroendocrine tumors. Observations on phenotypic and treatment-related associations.

Virchows Archiv : an international journal of pathology - 1 Aug 2023

Navale Pooja, Chatterjee Deyali, Itani Malak, Trikalinos Nikolaos A

Abstract excerpt

Pancreatic neuroendocrine tumors (PanNETs) in familial tuberous sclerosis (TSC1 and TSC2 mutations) have been known and studied. However, little is known about PanNET patients harboring the very rare (less than 2%) sporadic TSC mutations. Some renal tumors have been shown to harbor sporadic TSC mutations, with a distinctive morphological correlate. We hereby describe this rather unusual molecular alteration in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Capecitabine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney Neoplasms

Share to Mutation

Share to Neuroendocrine Tumors

Share to Pancreatic Neoplasms

Share to Temozolomide

Share to Tuberous Sclerosis

Source

Identifiers

PMID: 37354253
DOI: 10.1007/s00428-023-03570-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tuberous sclerosis complex mutations in patients with pancreatic neuroendocrine tumors. Observations on phenotypic and treatment-related associations.PMID 37354253Read ↗

Molecular pathology and genetics of pancreatic endocrine tumoursSemantic proximity Read ↗

Pancreatic neuroendocrine neoplasms: Updates on genomic changes in inherited tumour syndromes and sporadic tumours based on WHO classificationSemantic proximity Read ↗

Hereditary Syndromes Associated with Pancreatic and Lung Neuroendocrine TumorsSemantic proximity Read ↗

Genetics of Pancreatic Neuroendocrine Tumors.Semantic proximity Read ↗

Pancreatic neuroendocrine neoplasms (pNENs): Genetic and environmental biomarkers for risk of occurrence and prognosis.Semantic proximity Read ↗

Inherited syndromes involving pancreatic neuroendocrine tumorsSemantic proximity Read ↗

Pancreatic Neuroendocrine Neoplasms: 2020 Update on Pathologic and Imaging Findings and Classification.Semantic proximity Read ↗

Genomic landscape of pancreatic neuroendocrine tumours: the International Cancer Genome Consortium.Semantic proximity Read ↗

Pancreatic Neuroendocrine Neoplasms: Basic Biology, Current Treatment Strategies and Prospects for the FutureSemantic proximity Read ↗

Inherited pancreatic endocrine tumor syndromes: Advances in molecular pathogenesis, diagnosis, management, and controversiesSemantic proximity Read ↗

The landscape of molecular alterations in pancreatic and small intestinal neuroendocrine tumoursSemantic proximity Read ↗

A Direct Comparison of Patients With Hereditary and Sporadic Pancreatic Neuroendocrine Tumors: Evaluation of Clinical Course, Prognostic Factors and Genotype-Phenotype Correlations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.