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Article

Oxytocin system polymorphisms rs237887 and rs2740210 variants increase the risk of depression in pregnant women with early abuse.

Developmental psychobiology - 1 Jul 2023

Olazábal Daniel Ernesto, Bertoni Bernardo, Grandi Graciela, Musetti Dora, Rey Grazzia, Sandberg Natalia, Fernández Lucia, Laporte Gabriela, Medici Florencia, Nicolaisen-Sobesky Eliana

Abstract excerpt

Prepartum depression is associated with early adversity, pregnancy complications, preterm delivery, postpartum depression, and long-term effects on child neurodevelopment. The oxytocin (OXT) system is affected by early adverse experiences and has been associated with depression. In the current study, we investigated risk factors for prenatal depressive symptoms, mainly the effects of early childhood and...

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PMID: 37338248
DOI: 10.1002/dev.22400

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