Article
Impact of Single Nucleotide Polymorphisms of the Promoter of the TNF Gene on Adalimumab Treatment Responses in Hidradenitis Suppurativa.
Dermatology (Basel, Switzerland) - 1 Jan 2023
Argyropoulou Maria, Trigoni Anastasia, Kaffenberger Jessica, Stergianou Dimitra, Damoraki Georgia, Mingiani Elissavet, Micha Styliani, Krispinsky Andrew, Meltzanidou Parthena, Kanni Theodora, Lazaridou Elizabeth, Giamarellos-Bourboulis Evangelos J
Abstract excerpt
BACKGROUND: Results of randomized clinical trials show great variation in response to treatment with adalimumab (ADA) in hidradenitis suppurativa (HS). This varied response may be associated with genetic polymorphisms. OBJECTIVES: The aim of the study was to study the association between carriage of single nucleotide polymorphisms (SNPs) in the promoter of the tumor necrosis factor (TNF) gene and their response...
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