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Article

Identification and Validation of a Proliferation-Associated Score Model Predicting Survival in Lung Adenocarcinomas.

Disease markers - 1 Jan 2021

Bian Yunyi, Sui Qihai, Bi Guoshu, Zheng Yuansheng, Zhao Mengnan, Yao Guangyu, Xue Liang, Zhang Yi, Fan Hong

Abstract excerpt

AIM: This study is aimed at building a risk model based on the genes that significantly altered the proliferation of lung adenocarcinoma cells and exploring the underlying mechanisms. METHODS: The data of 60 lung adenocarcinoma cell lines in the Cancer Dependency Map (Depmap) were used to identify the genes whose knockout led to dramatical acceleration or deacceleration of cell proliferation. Then, univariate Cox...

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Identifiers

PMID: 34721732
DOI: 10.1155/2021/3219594
PMCID: PMC8554523

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