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Article

Genome editing of a rice CDP-DAG synthase confers multipathogen resistance.

Nature - 1 Jun 2023

Sha Gan, Sun Peng, Kong Xiaojing, Han Xinyu, Sun Qiping, Fouillen Laetitia, Zhao Juan, Li Yun, Yang Lei, Wang Yin, Gong Qiuwen, Zhou Yaru, Zhou Wenqing, Jain Rashmi, Gao Jie, Huang Renliang, Chen Xiaoyang, Zheng Lu, Zhang Wanying, Qin Ziting, Zhou Qi, Zeng Qingdong, Xie Kabin, Xu Jiandi, Chiu Tsan-Yu, Guo Liang, Mortimer Jenny C, Boutté Yohann, Li Qiang, Kang Zhensheng, Ronald Pamela C, Li Guotian

Abstract excerpt

The discovery and application of genome editing introduced a new era of plant breeding by giving researchers efficient tools for the precise engineering of crop genomes1. Here we demonstrate the power of genome editing for engineering broad-spectrum disease resistance in rice (Oryza sativa). We first isolated a lesion mimic mutant (LMM) from a mutagenized rice population. We then demonstrated that a 29-base-pair...

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Identifiers

PMID: 37316672
DOI: 10.1038/s41586-023-06205-2
PMCID: PMC11575942

Genes

RBL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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