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Doxorubicin inhibits phosphatidylserine decarboxylase and confers broad‐spectrum antifungal activity

6 May 2023

Abstract excerpt

As phospholipids of cell membranes, phosphatidylethanolamine (PE) and phosphatidylserine (PS) play crucial roles in glycerophospholipid metabolism. Broadly, some phospholipid biosynthesis enzymes serve as potential fungicide targets. Therefore, revealing the functions and mechanism of PE biosynthesis in plant pathogens would provide potential targets for crop disease control. We performed analyses including...

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PMID: 37148193
DOI: 10.1111/nph.18944

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