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Single-Cell Heterogeneity in Snake Venom Expression Is Hardwired by Co-Option of Regulators from Progressively Activated Pathways.

Genome biology and evolution - 1 Jun 2023

Westfall Aundrea K, Gopalan Siddharth S, Perry Blair W, Adams Richard H, Saviola Anthony J, Mackessy Stephen P, Castoe Todd A

Abstract excerpt

The ubiquitous cellular heterogeneity underlying many organism-level phenotypes raises questions about what factors drive this heterogeneity and how these complex heterogeneous systems evolve. Here, we use single-cell expression data from a Prairie rattlesnake (Crotalus viridis) venom gland to evaluate hypotheses for signaling networks underlying snake venom regulation and the degree to which different venom gene...

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PMID: 37311204
DOI: 10.1093/gbe/evad109
PMCID: PMC10289209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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