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Article

The Tiger Rattlesnake genome reveals a complex genotype underlying a simple venom phenotype.

Proceedings of the National Academy of Sciences of the United States of America - 26 Jan 2021

Margres Mark J, Rautsaw Rhett M, Strickland Jason L, Mason Andrew J, Schramer Tristan D, Hofmann Erich P, Stiers Erin, Ellsworth Schyler A, Nystrom Gunnar S, Hogan Michael P, Bartlett Daniel A, Colston Timothy J, Gilbert David M, Rokyta Darin R, Parkinson Christopher L

Abstract excerpt

Variation in gene regulation is ubiquitous, yet identifying the mechanisms producing such variation, especially for complex traits, is challenging. Snake venoms provide a model system for studying the phenotypic impacts of regulatory variation in complex traits because of their genetic tractability. Here, we sequence the genome of the Tiger Rattlesnake, which possesses the simplest and most toxic venom of any...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33468678
DOI: 10.1073/pnas.2014634118
PMCID: PMC7848695

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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