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Article

Progression, reliability, predicting parameters and sample size calculations for quantitative fundus autofluorescence measures in ABCA4-related retinopathy.

The British journal of ophthalmology - 21 May 2024

Müller Philipp L, Treis Tim, Tufail Adnan, Holz Frank G

Abstract excerpt

BACKGROUND/AIMS: To investigate the progression of quantitative autofluorescence (qAF) measures and the potential as clinical trial endpoint in ABCA4-related retinopathy. METHODS: In this longitudinal monocentre study, 64 patients with ABCA4-related retinopathy (age (mean±SD), 34.84±16.36 years) underwent serial retinal imaging, including optical coherence tomography (OCT) and qAF (488 nm excitation) imaging...

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PMID: 37286357
DOI: 10.1136/bjo-2022-322829

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