Article
Progression of Late-Onset Stargardt Disease.
Investigative ophthalmology & visual science - 1 Oct 2016
Lambertus Stanley, Lindner Moritz, Bax Nathalie M, Mauschitz Matthias M, Nadal Jennifer, Schmid Matthias, Schmitz-Valckenberg Steffen, den Hollander Anneke I, Weber Bernhard H F, Holz Frank G, van der Wilt Gert Jan, Fleckenstein Monika, Hoyng Carel B
Abstract excerpt
PURPOSE: Identification of sensitive biomarkers is essential to determine potential effects of emerging therapeutic trials for Stargardt disease. This study aimed to describe the natural history of late-onset Stargardt, and demonstrates the accuracy of retinal pigment epithelium (RPE) atrophy progression as an outcome measure. METHODS: We performed a retrospective cohort study collecting multicenter data from 47...
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