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Article

Quantitative Fundus Autofluorescence and Optical Coherence Tomography in ABCA4 Carriers.

Investigative ophthalmology & visual science - 1 Nov 2015

Duncker Tobias, Stein Gregory E, Lee Winston, Tsang Stephen H, Zernant Jana, Bearelly Srilaxmi, Hood Donald C, Greenstein Vivienne C, Delori François C, Allikmets Rando, Sparrow Janet R

Abstract excerpt

PURPOSE: To assess whether carriers of ABCA4 mutations have increased RPE lipofuscin levels based on quantitative fundus autofluorescence (qAF) and whether spectral-domain optical coherence tomography (SD-OCT) reveals structural abnormalities in this cohort. METHODS: Seventy-five individuals who are heterozygous for ABCA4 mutations (mean age, 47.3 years; range, 9-82 years) were recruited as family members of...

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Identifiers

PMID: 26551331
DOI: 10.1167/iovs.15-17371
PMCID: PMC4642605

Genes

ABCA4
RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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