Article
Increased prevalence and stable clustering rate of HIV-1 transmitted drug resistance strains after 'treat-all' in a megacity of China.
The Journal of antimicrobial chemotherapy - 5 Jul 2023
Zhang Dong, Han Jingwan, Li Hanping, Zheng Chenli, Liu Zhi, Sun Zixuan, Li Hao, Li Tianyi, Wang Xiaolin, Chen Lin, Yang Zhengrong, Lan Chunlin, Li Siqi, Jia Lei, Gan Yongxia, Zhong Yifan, Li Jingyun, Li Lin, Zhao Jin
Abstract excerpt
OBJECTIVES: The 'treat-all' strategy was implemented in Shenzhen, China in 2016. The effect of this extensive treatment on transmitted drug resistance (TDR) of HIV is unclear. METHODS: TDR analysis was performed, based on the partial HIV-1 pol gene obtained from the newly reported HIV-1 positive cases from 2011 to 2019 in Shenzhen, China. The HIV-1 molecular transmission networks were inferred to analyse the...
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