Geographical and temporal trends of HIV-1 subtypes and drug resistance in China: a nationwide study over two decades (2003-2024).

doi:10.1099/jgv.0.002217

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Article

Geographical and temporal trends of HIV-1 subtypes and drug resistance in China: a nationwide study over two decades (2003-2024).

The Journal of general virology - 1 Feb 2026

Xie Bin, Wang Zhenggang, Song Qixiang, Cui Miao, Deng Yelin, Zheng Fang, Krol Ewelina, Khouri Ricardo, De Clercq Erik, Mo Juan, Li Guangdi

Abstract excerpt

Objective. This study aims to characterize the 20-year trends in human immunodeficiency virus 1 (HIV-1) subtypes and circulating recombinant forms (CRFs) in China, as well as patterns of transmitted drug resistance (TDR) to antiretroviral therapies commonly used in clinical practice.Methods. We analysed HIV-1 sequences from 81,563 individuals living in China between 2003 and 2024. Subtypes and CRFs were...

Topics

HIV-1
Humans
China
Drug Resistance, Viral
HIV Infections
Genotype
Anti-HIV Agents
Phylogeny
Female
Male
Adult
Prevalence

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Identifiers

PMID: 41627869
DOI: 10.1099/jgv.0.002217
PMCID: PMC12865022

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