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Article

The Utility of ctDNA in Lung Cancer Clinical Research and Practice: A Systematic Review and Meta-Analysis of Clinical Studies.

Cancer investigation - 1 Jul 2023

Sun Xuezheng, Abrahamson Page, Ballew Nicholas, Kalilani Linda, Phiri Kelesitse, Bell Kelly F, Slowley Alexander, Zajac Magdalena, Hofstatter Erin, Stojadinovic Alexander, Silvestro Angela, Wang Zebin, Aziez Amine, Peters Solange

Abstract excerpt

This systematic review with embedded meta-analysis aimed to evaluate the clinical utility of circulating tumor DNA (ctDNA) in lung cancer. After screening and review of the Embase database search, 111 studies from 2015 to 2020 demonstrated ctDNA's value in prognostication/monitoring disease progression, mainly in patients with advanced/metastatic disease and non-small cell lung cancer. ctDNA positivity/detection...

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Identifiers

PMID: 37272675
DOI: 10.1080/07357907.2023.2220820

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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