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Article

The prognostic role of circulating DNA markers in patients with lung malignancies: a systematic review and meta-analysis.

Biomarkers in medicine - 1 Aug 2025

Kazemi-Harikandei Sayedeh-Zahra, Salmani Jelodar Mohammad-Reza, Roshandel Gholamreza, Tavangar Seyed Mohammad

Abstract excerpt

AIMS: We aimed to explore the prognostic role of circulating DNA-related markers to improve clinical decision-making in patients with lung malignancies. METHODS: A systematic search was performed on PubMed, Scopus, and Web of Science. RESULTS: About 133 articles were included, comprising 5750 EGFR-positive, 1583 ALK-positive, and 9657 patients without specified genetic groups. Circulating tumor DNA (ctDNA)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40825939
DOI: 10.1080/17520363.2025.2548190
PMCID: PMC12416206

Genes

EGFR
ALK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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