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Protein production from HEK293 cell line-derived stable pools with high protein quality and quantity to support discovery research

2 Jun 2023

Abstract excerpt

Antibody-based therapeutics and recombinant protein reagents are often produced in mammalian expression systems, which provide human-like post-translational modifications. Among the available mammalian cell lines used for recombinant protein expression, Chinese hamster ovary (CHO)-derived suspension cells are generally utilized because they are easy to culture and tend to produce proteins in high yield. However,...

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PMID: 37267316
DOI: 10.1371/journal.pone.0285971

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