Article
Efficacy and safety of pan-genotypic sofosbuvir and velpatasvir in patients with hepatitis C and HIV coinfection on dolutegravir-based antiretroviral therapy.
Journal of viral hepatitis - 1 Sept 2023
De Arka, Charak Swati, Bhagat Naveen, Rathi Sahaj, Verma Nipun, Premkumar Madhumita, Taneja Sunil, Sharma Aman, Goel Kapil, Singh Virendra, Duseja Ajay
Abstract excerpt
Hepatitis C virus (HCV) infection is more prevalent in people living with HIV-AIDS (PLHA) and portends a poorer prognosis. Pharmacokinetic studies suggest the absence of significant interaction between velpatasvir and dolutegravir which has been recently recommended as part of preferred first-line antiretroviral therapy (ART) regimens by WHO. However, clinical data on the use of velpatasvir-based regimen in PLHA...
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