Article
Pharmacokinetic drug evaluation of velpatasvir plus sofosbuvir for the treatment of hepatitis C virus infection.
Expert opinion on drug metabolism & toxicology - 1 Apr 2017
Brieva Teresa, Rivero Antonio, Rivero-Juarez Antonio
Abstract excerpt
INTRODUCTION: The fixed-dose combination therapy of sofosbuvir (SOF) plus velpatasvir (VEL) is the first pangenotypic, direct-acting antiviral (DAA), single-treatment regimen (STR) for the treatment of hepatitis C virus (HCV) infection to be commercialized. It is approved for the treatment of HCV genotypes 1, 2, 3, 4, 5, and 6. Following approval in 2016, new pharmacokinetic and pharmacodynamic data were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
