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Article

Telomere shortening as a hallmark of stem cell senescence

1 Mar 2019

Abstract excerpt

Stem cells, especially mesenchymal stem cells (MSCs)-based therapies have been greatly attentioned in regenerative medicine through multi-lineage differentiation, self-renewal properties, etc. Despite the above advantages of MSCs, the defined properties of these cells are strongly affected by aging. Thus, the use of MSCs from older donors is lower than younger one, which limits clinical applications in cell...

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Share to Circadian rhythm and melatonin
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Telomeres, Telomerase, and Senescence

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PMID: 31019963
DOI: 10.21037/sci.2019.02.04

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