Article
The characteristics and clinical relevance of tumor fusion burden in non-EBV (+) gastric cancer with MSS.
BMC gastroenterology - 15 May 2023
Zhu Yongjun, Wu Weixin, Qiao Liangliang, Ji Jingfen, Duan Lunxi, Gong Longlong, Ren Dandan, Li Feifei, Wei Lihui, Pan Ke
Abstract excerpt
BACKGROUND: Next-generation sequencing (NGS) is maturely applied for gene fusion detection. Although tumor fusion burden (TFB) has been identified as an immune marker for cancer, the relationship between these fusions and the immunogenicity and molecular characteristics of gastric cancer (GC) patients remains unclear. GCs have different clinical significance depending on their subtypes, and thus, this study aimed...
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