Article
Phenotypic and Endotypic Determinants of Atopic Dermatitis Severity From the Atopic Dermatitis Research Network (ADRN) Registry.
The journal of allergy and clinical immunology. In practice - 1 Aug 2023
Simpson Eric L, De Benedetto Anna, Boguniewicz Mark, Ong Peck Y, Lussier Stephanie, Villarreal Miguel, Schneider Lynda C, Paller Amy S, Guttman-Yassky Emma, Hanifin Jon M, Spergel Jonathan M, Barnes Kathleen C, David Gloria, Austin Briahnna, Leung Donald Y M, Beck Lisa A
Abstract excerpt
BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin condition with a highly variable clinical phenotype. OBJECTIVE: This study aimed to identify historical and clinical features and biomarkers associated with AD severity. METHODS: A US registry of extensively phenotyped AD participants (aged 0.73-80 years) were enrolled at 9 academic centers. Information on family and personal medical history,...
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