Article
PROTACs in the Management of Prostate Cancer.
Molecules (Basel, Switzerland) - 25 Apr 2023
Yedla Poornachandra, Babalghith Ahmed O, Andra Vindhya Vasini, Syed Riyaz
Abstract excerpt
Cancer treatments with targeted therapy have gained immense interest due to their low levels of toxicity and high selectivity. Proteolysis-Targeting Chimeras (PROTACs) have drawn special attention in the development of cancer therapeutics owing to their unique mechanism of action, their ability to target undruggable proteins, and their focused target engagement. PROTACs selectively degrade the target protein...
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