Article
Regulation of dendritic cell maturation in osimertinib-treated lung adenocarcinoma patients.
Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Sept 2023
Wu Ming-Fang, Chang Ya-Hsuan, Chen Hsuan-Yu, Ho Chao-Chi, Chen Huei-Wen
Abstract excerpt
Osimertinib (OSI), a third-generation tyrosine kinase inhibitor (TKI), efficiently benefits lung adenocarcinoma (LUAD) patients with epidermal growth factor receptor (EGFR) mutations. However, combined OSI and immune checkpoint inhibitor in EGFR-mutant patients increases the incidence of interstitial lung disease (ILD), although the mechanism is unknown. Here, we investigated the interaction between dendritic...
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