Article
Effect of CYP2D6 pharmacogenetic phenotype and phenoconversion on serum concentrations of antidepressants and antipsychotics: a retrospective cohort study.
International journal of clinical pharmacy - 1 Oct 2023
Scherf-Clavel Maike, Frantz Amelie, Eckert Andreas, Weber Heike, Unterecker Stefan, Deckert Jürgen, Reif Andreas, Hahn Martina
Abstract excerpt
BACKGROUND: Pharmacogenetics (PGx), especially in regard to CYP2D6, is gaining more importance in routine clinical settings. Including phenoconversion effects (PC) in result interpretation could maximize its potential benefits. However, studies on genetics of pharmacokinetic genes including the functional enzyme status are lacking. AIM: The retrospective analyses of clinical routine data aimed to investigating...
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