Article
Reduced Exercise Capacity, Chronotropic Incompetence, and Early Systemic Inflammation in Cardiopulmonary Phenotype Long Coronavirus Disease 2019.
The Journal of infectious diseases - 31 Aug 2023
Durstenfeld Matthew S, Peluso Michael J, Kaveti Punita, Hill Christopher, Li Danny, Sander Erica, Swaminathan Shreya, Arechiga Victor M, Lu Scott, Goldberg Sarah A, Hoh Rebecca, Chenna Ahmed, Yee Brandon C, Winslow John W, Petropoulos Christos J, Kelly J Daniel, Glidden David V, Henrich Timothy J, Martin Jeffrey N, Lee Yoo Jin, Aras Mandar A, Long Carlin S, Grandis Donald J, Deeks Steven G, Hsue Priscilla Y
Abstract excerpt
BACKGROUND: Mechanisms underlying persistent cardiopulmonary symptoms after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (postacute sequelae of coronavirus disease 2019 [COVID-19; PASC] or "long COVID") remain unclear. This study sought to elucidate mechanisms of cardiopulmonary symptoms and reduced exercise capacity. METHODS: We conducted cardiopulmonary exercise testing (CPET), cardiac...
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