Article
Short-term efficacy and safety of personalized antiplatelet therapy for patients with acute ischaemic stroke or transient ischaemic attack: A randomized clinical trial.
British journal of clinical pharmacology - 1 Sept 2023
Han Mengqi, Jia Weijie, Wu Yifan, Kuang Jie, Tu Jianglong, Yin Shujuan, Chen Jibiao, Zhang Xiaolin, Li Jingyi, Chen Yongsen, Wu Bin, Yi Yingping
Abstract excerpt
AIMS: The aim of this study was to determine whether the testing strategy for clopidogrel and/or aspirin resistance using CYP2C19 genotyping or urinary 11-dhTxB2 testing has an impact on clinical outcomes. METHODS: A multicentre, randomized, controlled trial was conducted at 14 centres in China from 2019 to 2021. For the intervention group, a specific antiplatelet strategy was assigned based on the CYP2C19...
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