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Recent progress of aptamer‒drug conjugates in cancer therapy

26 Jan 2023

Abstract excerpt

Aptamers are single-stranded DNA or RNA sequences that can specifically bind with the target protein or molecule via specific secondary structures. Compared to antibody-drug conjugates (ADC), aptamer‒drug conjugate (ApDC) is also an efficient, targeted drug for cancer therapy with a smaller size, higher chemical stability, lower immunogenicity, faster tissue penetration, and facile engineering. Despite all these...

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PMID: 37139427
DOI: 10.1016/j.apsb.2023.01.017

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