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Evolutionary investigations of the biosynthetic diversity in the skin microbiome using lsaBGC

28 Apr 2023

Abstract excerpt

Bacterial secondary metabolites, synthesized by enzymes encoded in biosynthetic gene clusters (BGCs), can underlie microbiome homeostasis and serve as commercialized products, which have historically been mined from a select group of taxa. While evolutionary approaches have proven beneficial for prioritizing BGCs for experimental characterization efforts to uncover new natural products, dedicated bioinformatics...

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PMID: 37115189
DOI: 10.1099/mgen.0.000988

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