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Article

The 3' UTR polymorphisms rs3742330 in DICER1 and rs10719 in DROSHA genes are not associated with primary open-angle and angle-closure glaucoma: As case-control study.

PloS one - 1 Jan 2023

Kondkar Altaf A, Azad Taif A, Sultan Tahira, Osman Essam A, Almobarak Faisal A, Lobo Glenn P, Al-Obeidan Saleh A

Abstract excerpt

AIM: In a retrospective and exploratory case-control study, we examined the genetic association of two common polymorphisms in the 3' untranslated region (UTR) of DICER1 (rs3742330) and DROSHA (rs10719) genes in primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG), and its related clinical phenotypes in a Saudi cohort. METHODS: DNA genotyping was performed using TaqMan real-time PCR assays...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to 3' Untranslated Regions
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Share to DEAD-box RNA Helicases
Share to Glaucoma, Angle-Closure
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Share to Polymorphism, Single Nucleotide
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Identifiers

PMID: 37099569
DOI: 10.1371/journal.pone.0284852
PMCID: PMC10132650

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