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Article

Ezogabine impacts seizures and development in patients with KCNQ2 developmental and epileptic encephalopathy.

Epilepsia - 1 Jul 2023

Knight Devon, Mahida Sonal, Kelly Mckenna, Poduri Annapurna, Olson Heather E

Abstract excerpt

Genetic variants in KCNQ2 are associated with a range of epilepsies, from self- limited (familial) neonatal-infantile epilepsy to developmental and epileptic encephalopathy (DEE). We retrospectively reviewed clinical data from eight patients with KCNQ2-related DEE who were treated with ezogabine. Treatment was initiated at a median age of 8 months (range, 7 weeks to 2.5 years) and continued for a median of...

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Source

Identifiers

PMID: 37096745
DOI: 10.1111/epi.17627

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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