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Article

Mutant-allele dispersion correlates with prognosis risk in patients with advanced non-small cell lung cancer.

Journal of cancer research and clinical oncology - 1 Sept 2023

Wang Chen-Xu, Yan Jie, Lin Shan, Ding Yi, Qin Yan-Ru

Abstract excerpt

BACKGROUND: Intra-tumor heterogeneity (ITH) contributes to lung cancer progression and resistance to therapy. To evaluate ITH and determine whether it may be employed as a predictive biomarker of prognosis in patients with advanced non-small cell lung cancer (NSCLC), we used a novel algorithm called mutant-allele dispersion (MAD). METHODS: In the study, 103 patients with advanced NSCLC were enrolled. Using a...

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Identifiers

PMID: 37093348
DOI: 10.1007/s00432-023-04801-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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