Article
[Olaparib Could Be Re-Administered after Chemotherapy].
Gan to kagaku ryoho. Cancer & chemotherapy - 1 Apr 2023
Terasawa Risa, Takashima Yuko, Hirata Aoko, Kimura Kousei, Morita Shinsho, Hayashi Michihiro
Abstract excerpt
Olaparib, a PARP inhibitor, was approved in 2018 for BRCA1/2 gene mutation and HER2-negative inoperable or recurrent breast cancer with previous chemotherapy. Olaparib is an important drug with minor adverse events compared to chemotherapeutic drugs. In addition, it is expected to exert a high therapeutic effect on breast cancer with BRCA mutations due to its characteristics. We report a case of BRCA2-mutated...
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