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Getting closer to modeling the gut-brain axis using induced pluripotent stem cells

31 Mar 2023

Abstract excerpt

The gut microbiome (GM), the gut barrier, and the blood-brain barrier (BBB) are key elements of the gut-brain axis (GBA). The advances in organ-on-a-chip and induced pluripotent stem cell (iPSCs) technology might enable more physiological gut-brain-axis-on-a-chip models. The ability to mimic complex physiological functions of the GBA is needed in basic mechanistic research as well as disease research of...

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PMID: 37065853
DOI: 10.3389/fcell.2023.1146062

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