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White coat color of a Black Angus calf attributed to an occurrence of the delR217 variant of MITF.

Animal genetics - 1 Aug 2023

Petersen Jessica L, Sieck Renae L, Steffen David J

Abstract excerpt

A white calf, with minimal pigmented markings, was born to two registered Black Angus parents. Given the possibility of an unknown recessive or de novo dominant mutation, whole-genome sequencing was conducted on the trio of individuals. A 3-bp in-frame deletion in MITF was identified; this mutation was unique to the calf but identical to the delR217 variant reported in both humans and murine models of Waardenburg...

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PMID: 37062854
DOI: 10.1111/age.13327

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