Article
High expression of the classical swine fever virus (CSFV) envelope protein E2 by a single amino acid mutation and its embedded in the pseudorabies virus (PRV) vector for immunization.
Virus research - 2 Jul 2023
Sun Yang-Yang, Liu Ke-Shu, Yun Tao, Ni Zheng, Zhu Yin-Chu, Chen Liu, Bao Hai-Li, Ye Wei-Cheng, Hua Jiong-Gang, Huo Su-Xin, Wang Hong-Yu, Bao En-Dong, Zhang Cun
Abstract excerpt
Pseudorabies (PR) and classical swine fever (CSF) are economically important infectious diseases in pigs. Most pig farms in China are vaccinated against these two diseases. Gene-deleted pseudorabies virus (PRV) can be used to develop promising and economical multivalent live attenuated viral vector vaccines. It has been reported that recombinant PRV can express a truncated E2 protein (1-338 aa), but it has not...
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