Article
Modeling the Effects of Cypermethrin Toxicity on Ovalbumin-Induced Allergic Pneumonitis Rats: Macrophage Phenotype Differentiation and p38/STAT6 Signaling Are Candidate Targets of Pirfenidone Treatment.
Cells - 24 Mar 2023
Morsi Ahmed A, Faruk Eman Mohamed, Mogahed Mysara Mohamed, Baioumy Bodour, Hussein Asmaa Y A, El-Shafey Rabab Shaban, Mersal Ezat A, Abdelmoneim Ahmed M, Alanazi Mohammed M, Elshazly Amal Mahmoud ElSafy
Abstract excerpt
Although the classic form of asthma is characterized by chronic pneumonitis with eosinophil infiltration and steroid responsivity, asthma has multifactorial pathogenesis and various clinical phenotypes. Previous studies strongly suggested that chemical exposure could influence the severity and course of asthma and reduce its steroid responsiveness. Cypermethrin (CYP), a common pesticide used in agriculture, was...
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