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Article

Smooth Muscle Cell Phenotypic Switch Induced by Traditional Cigarette Smoke Condensate: A Holistic Overview.

International journal of molecular sciences - 29 Mar 2023

Bianchi Laura, Damiani Isabella, Castiglioni Silvia, Carleo Alfonso, De Salvo Rossana, Rossi Clara, Corsini Alberto, Bellosta Stefano

Abstract excerpt

Cigarette smoke (CS) is a risk factor for inflammatory diseases, such as atherosclerosis. CS condensate (CSC) contains lipophilic components that may represent a systemic cardiac risk factor. To better understand CSC effects, we incubated mouse and human aortic smooth muscle cells (SMCs) with CSC. We evaluated specific markers for contractile [i.e., actin, aortic smooth muscle (ACTA2), calponin-1 (CNN1), the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37047404
DOI: 10.3390/ijms24076431
PMCID: PMC10094728

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