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Safety and immunogenicity of a TK/ gI/gE gene-deleted feline herpesvirus-1 mutant constructed via CRISPR/Cas9 in feline

21 Mar 2023

Abstract excerpt

Feline herpesvirus-1 (FHV-1) is the aetiological agent of feline viral rhinotracheitis, which accounts for approximately 50 % of all viral upper respiratory diseases in cats. Commercially available modified live vaccines containing FHV-1 are generally safe and effective, but these FHV-1 vaccines retain full virulence genes and can establish latency and reactivate to cause infectious rhinotracheitis in vaccine...

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Cytomegalovirus and herpesvirus research
Herpesvirus Infections and Treatments
Virus-based gene therapy research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37003192
DOI: 10.1016/j.vetmic.2023.109728

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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